Meet the Lab

Photo Credit:  Peter Hellberg

Dori Woods, Ph.D., Principal Investigator

Associate Professor and Director of Graduate Studies
Department of Biology
College of Science

Affiliated Faculty
Department of Bioengineering
College of Engineering


Phone: (617)373-2851


Ph.D., University of Notre Dame, 2007
B.S., University of Arizona, 2001

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Yukiko Mikami, MD, Ph.D.

My research project focuses on the differentiation of oogonial stem cells (OSCs) and reconstitution of autologous ovarian tissue. Aggregation of OSCs with primitive granulosa cells, isolated ovarian tissue during OSC purification, enables de-novo oogenesis and folliculogenesis in the reconstituted tissue in vitro. We hope our research may be helpful to better understand oogenesis and be ray of light for infertility and/or oncofertility treatments.

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Hannah Sheehan, Graduate Student

My work focuses on developing an understanding of the physiological role mitochondrial subpopulations play in cellular processes. By characterizing these mitochondrial subpopulations, we hope to better understand their function in the progression of disease, aging, and infertility.

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Charles Linskey, Graduate Student

My work is focused on understanding the role mitochondria may be playing in a recently identified medical condition (Fluoroquinolone-Associated Disability) which causes debilitating side-effects in a number of patients who take fluoroquinolone-class antibiotics (such as ciprofloxacin, nevofloxacin, or levofloxacin). By characterizing the dysfunction of mitochondria in cells and models exposed to these antibiotics we hope to better understand mitochondrial dysfunction in general which is a feature of many diseases, as well as the effects of fluroquinolones specifically, in a way that may someday lead to novel treatments for patients.


Julie MacDonald (Tilly Lab), PhD, Post Doctoral Research Associate

My research project is on the influence of the physical environment on cellular function and differentiation.  Utilizing emerging technologies in bioengineering and mechanobiology allows for new insights into the role played by extracellular matrix proteins, as both components of cell signaling pathways as well as transducers of mechanical strain to better understand the adult oogonial stem cell population, and how its dynamics may change with age.

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Jessica Martin (Tilly Lab), Graduate Student

I am interested in the characterization of mitochondria in mouse preimplantation embryos to better understand mitochondrial allocation. My focus is on understanding how mitochondrial allocation throughout development can lead to lineage specification within the preimplantation embryo and how it impacts female fertility, specifically in aging women.


Undergraduates and Visiting Students

We have a lively and constant stream of undergraduate students coming through the lab either as volunteers, work study students, independent studies, and NSF-sponsored REU participants.

Current Summer 2019 Undergraduate Lab Members:

  • Efosa Enoma (Co-op)

  • Fausto Capelluto (BS/Ph.D. Student)

  • Bailey Smith (Volunteer)

  • Sam Eun (REU Participant)

  • Tia Hoisington (REU Participant)

  • Conner Shaughnessy (Volunteer and directed study)

  • Leah Simmons (Co-op, Fall 2015)

  • Alyssa Kania (Directed study)

  • Shalin Shetty (Directed study)

  • Leannah Newman (Volunteer)

  • Brook Simonton (Capstone study)

  • Alexa DelBene (Volunteer)

  • Quiyi Wang (Volunteer)

  • Nick Solek (Volunteer)

  • Emma Robinson (Volunteer)

  • Rachael Sverdlove (Directed study)

Past Students and Graduating Seniors:

  • Carleigh Sussman (Directed study)

  • Niharika Kura (Volunteer and Directed study)

  • Joyce Jin (Volunteer)

  • Tanner Eggert (Directed Study)

  • Christina Yung (Volunteer and Research technician)

  • Menaka Sanghvi (Directed study)

  • Shandy Maccow (Volunteer)

  • Irena Kuzma (Volunteer and directed study)

  • Dominick Pezzulo (Volunteer)

  • Christina Weber (Co-op)

  • Katie Izzo (Volunteer)

  • Monika Izdebski (Co-op, Fall 2015)

  • Katharina Winkel (2015-2016 Master's student, Hannover, Germany exchange)

Lab Alumni

  • Taichi Akahori, MD, Ph.D.

  • Alisha (Truman) Bothun, Ph.D.

  • Paulo Henrique de Almeida Campos-Junior, Ph.D.

  • Christine Faraci, M.S.

  • Anna Denicol, DVM, Ph.D. - Assistant Professor at University of California, Davis

  • Deanna Navaroli, Ph.D.

  • Kshama Chandrasekhar, Ph.D.